SGPT stands for Serum Glutamic Pyruvic Transaminase.
It’s also known as Alanine Aminotransferase (ALT).
Essentially, SGPT is an enzyme found mostly in the liver, but also in smaller amounts in the heart, kidneys, and muscles. When your liver is damaged, it releases SGPT into your bloodstream. Therefore, an SGPT test measures the level of this enzyme in your blood, which can help doctors assess liver health and detect potential issues.
High SGPT levels may indicate:
- Liver damage due to various factors such as:
- Viral hepatitis (Hepatitis A, B, or C)
- Non-alcoholic fatty liver disease (NAFLD)
- Alcohol abuse
- Certain medications
- Autoimmune diseases
- Heart problems
- Muscle damage
Function
SGPT plays a role in the metabolism of amino acids and production of energy. It helps convert alanine, an amino acid, into pyruvate, which is used in energy production.
Medical Relevance
SGPT levels are measured through blood tests. Elevated levels can indicate liver damage or inflammation, often used to diagnose conditions such as:
- Hepatitis
- Fatty liver disease
- Alcoholic liver disease
- Cirrhosis
Normal Levels
Normal SGPT levels typically range from 7 to 56 units per liter of blood. The normal range can vary based on age, gender, and specific laboratory standards.
Factors Affecting SGPT Levels
- Medications
- Alcohol consumption
- Obesity
- Viral infections
Conclusion
Monitoring SGPT levels is crucial for maintaining liver health and diagnosing potential liver-related health issues. Always consult healthcare professionals for accurate diagnosis and tailored medical advice.