fc receptor full form

FC Receptor Full Form

FC Receptor stands for Fragment Crystallizable Receptor.

Key Points:

• Function: FC receptors are proteins found on the surface of certain immune cells, such as macrophages, dendritic cells, and B cells. They play a crucial role in the immune response by binding to the Fc region of antibodies.

• Types of FC Receptors:

• FcγR: Binds to IgG antibodies.
• FcεR: Binds to IgE antibodies.
• FcαR: Binds to IgA antibodies.

• FcμR: Binds to IgM antibodies.

• Importance in Immunology:

• They facilitate phagocytosis of pathogens.
• They mediate antibody-dependent cellular cytotoxicity (ADCC).

• They help in the regulation of adaptive immune responses.

• Clinical Relevance:

• Alterations in FC receptor functions can lead to autoimmune diseases or immunodeficiencies.
• FC receptors are also targets in therapeutic antibody design, enhancing the effectiveness of treatments for various diseases.

Understanding FC receptors is essential for grasping how the immune system recognizes and responds to pathogens, as well as for the development of immunotherapies.